Cyanocobalamin (B12)
Vitamin B12 is necessary for processing carbohydrates, proteins and fats and to help make all of the blood cells in our bodies. Vitamin B12 is also required for maintenance of our nerve sheaths. Vitamin B12 acts as a coenzyme in the synthesis and repair of DNA.
Vitamin B12 cannot be absorbed or used by the body until it is combined with a mucoprotein made in the stomach and called intrinsic factor. Once the B12 becomes bound to the intrinsic factor, it is able to pass into the small intestine to be absorbed and used by the body. Vitamin B12 deficiency is sometimes seen in strict vegetarians who do not take vitamin supplements, and those who have an inability to absorb the vitamin (usually from a failure to produce intrinsic factor). Although enough B12 is stored in the liver to sustain a person for many years, a deficiency will cause a disorder known as pernicious anemia. Pernicious anemia causes weakness, numbness of the extremities, pallor, fever and other symptoms. Mouth irritation and brain damage are also common consequences of B12 deficiency. However, these very serious effects can be reversed by vitamin B12 shots. Shots are needed because the deficiency is often caused by an inability to absorb the vitamin when taken orally. As we age, our stomachs have an increasingly difficult time producing intrinsic factor. Many doctors recommend that people over 60 have their vitamin B12 levels checked, to see if a B12 shot is needed.
Vitamin B12 is not found in any plant food sources and is produced almost solely by bacteria, such as streptomyces griseus. Rich sources of B12 include liver, meat, egg yolk, poultry and milk.
What can cause problems with absorbing vitamin B-12?
The following are some things that can cause problems with absorbing vitamin B-12:
If you have a disease called pernicious anemia (say: "per-nish-us ah-nee-mee-ah"), it can destroy the cells in your stomach that help you absorb vitamin B-12.
If you use medicine for heartburn and ulcers for a long time, you may have trouble absorbing vitamin B-12.
If you have had surgery on your stomach or your intestines, you may have trouble absorbing vitamin B-12.
Your doctor will find out why you have a low vitamin B-12 level by asking questions about your health, giving you a physical exam and checking your blood, if necessary.
Can I just take one multivitamin pill every day to raise a low vitamin B-12 level?
No. Over-the-counter multivitamins do not contain enough vitamin B-12 to raise a low level. To get enough vitamin B-12, you will need to take special vitamin B-12 pills.
You can also get shots of vitamin B-12. Usually, these shots are given every 1 to 2 days for about 2 weeks. After this, a shot is given once every month. Your doctor can help decide whether pills or shots are right for you.
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